Manchester United Football Club is an English association football club based in Old Trafford, Greater Manchester, that competes in the Premier League. Founded as Newton Heath LYR Football Club in 1878, the club changed its name to Manchester United in 1902. During the 1889–90 season, Manchester United joined the Football Alliance. The team was elected to The Football League in 1892, where the club remained until 1992, when the League's First Division was replaced as the top level of English football by the Premier League.

Manchester United's first team has competed in a number of nationally contested leagues, and its record against each club faced in these competitions is listed below. In total, Red Devils had 88 different league opponents.

The team that Manchester United has met most in league competition is Arsenal, against whom they have contested 210 league matches (as of the end of the 2023–24 season). In those games United have suffered 76 league defeats, which represents the most they have lost against any club, as well as conceded 295 goals – also club record. Manchester United have won more league matches (91) and scored more league goals (321) against Aston Villa than they have against any other club. Out of the 164 league matches between Manchester United and Chelsea, 53 have been drawn (32.3%) – more than with any other club.

• The records include the results of matches played in the Football Alliance (from 1889 to 1892), The Football League (from 1892 to 1992) and the Premier League (since 1992). Wartime matches are regarded as unofficial and are excluded, as are matches from the abandoned 1888–89 and 1939–40 seasons. Test Matches are not included.
• For the sake of simplicity, present-day names are used throughout: for example, results against Ardwick, Small Heath and Woolwich Arsenal are integrated into the records against Manchester City, Birmingham City and Arsenal, respectively.
•    † Teams with this background and symbol in the "Club" column are competing in the 2024–25 Premier League alongside Manchester United.
•    ‡ Clubs with this background and symbol in the "Club" column are defunct.
• Pld = matches played; W = matches won; D = matches drawn; L = matches lost; GF = Goals for; GA = Goals against; GD = Goal difference; Win% = percentage of total matches won

As of match played on 27 October 2024

Manchester United league record by opponent

Club	Home				Away				Total								Ref(s)
	Pld	W	D	L	Pld	W	D	L	Pld	W	D	L	GF	GA	GD	Win%
Accrington ‡	1	0	1	0	1	0	1	0	2	0	2	0	5	5	0		0.00
Arsenal †	105	59	29	17	105	26	20	59	210	85	49	76	315	295	20	40.48
Aston Villa †	88	59	17	12	89	32	24	33	177	91	41	45	321	227	94	51.41
Barnsley	16	13	2	1	16	6	7	3	32	19	9	4	64	21	43	59.38
Birmingham City	47	30	8	9	47	13	19	15	94	43	27	24	138	101	37	45.74
Birmingham St George's ‡	3	2	0	1	3	1	0	2	6	3	0	3	11	16	–5	50.00
Blackburn Rovers	49	28	11	10	49	17	14	18	98	45	25	28	183	140	43	45.92
Blackpool	41	27	8	6	41	18	9	14	82	45	17	20	156	98	58	54.88
Bolton Wanderers	59	33	10	16	59	19	15	25	118	52	25	41	192	156	36	44.07
Bootle ‡	3	3	0	0	3	0	1	2	6	3	1	2	11	11	0	50.00
Bournemouth †	7	5	1	1	7	4	1	2	14	9	2	3	28	15	13	64.29
Bradford City	23	15	6	2	23	7	7	9	46	22	13	11	78	37	41	47.83
Bradford Park Avenue	9	5	0	4	9	3	1	5	18	8	1	9	30	36	–6	44.44
Brentford †	9	6	1	2	8	3	2	3	17	9	3	5	31	27	4	52.94
Brighton & Hove Albion †	11	8	1	2	12	5	1	6	23	13	2	8	35	25	10	56.52
Bristol City	17	9	3	5	17	5	7	5	34	14	10	10	47	39	8	41.18
Bristol Rovers	1	1	0	0	1	0	1	0	2	1	1	0	3	1	2	50.00
Burnley	60	34	12	14	60	23	10	27	120	57	22	41	207	169	38	47.5
Burton Swifts ‡	7	4	3	0	7	3	1	3	14	7	4	3	36	21	15	50.00
Burton United ‡	6	5	1	0	6	3	2	1	12	8	3	1	29	10	19	66.67
Burton Wanderers ‡	3	1	1	1	3	1	0	2	6	2	1	3	8	10	–2	33.33
Bury ‡	19	9	2	8	19	10	5	4	38	19	7	12	58	46	12	50.00
Cardiff City	15	6	6	3	15	9	2	4	30	15	8	7	59	42	17	50.00
Charlton Athletic	28	20	5	3	28	15	6	7	56	35	11	10	113	59	54	62.50
Chelsea †	82	34	29	19	82	31	24	27	164	65	53	46	261	201	60	39.63
Chesterfield	10	10	0	0	10	3	1	6	20	13	1	6	41	22	19	65.00
Coventry City	37	23	8	6	37	16	8	13	74	39	16	19	124	70	54	52.70
Crewe Alexandra	5	4	0	1	5	4	1	0	10	8	1	1	32	11	21	80.00
Crystal Palace †	27	19	3	5	28	13	9	6	55	32	12	11	91	50	41	58.18
Darwen ‡	8	6	1	1	8	2	2	4	16	8	3	5	35	22	13	50.00
Derby County	45	24	10	11	45	12	17	16	90	36	27	27	157	136	21	40.00
Doncaster Rovers	4	3	1	0	4	1	2	1	8	4	3	1	19	6	13	50.00
Everton †	95	54	25	16	95	31	21	43	190	85	46	59	285	257	28	44.74
Fulham †	39	31	5	3	38	17	11	10	77	48	16	13	152	80	72	62.34
Gainsborough Trinity	10	8	2	0	10	5	3	2	20	13	5	2	36	14	22	65.00
Glossop North End	7	6	1	0	7	5	1	1	14	11	2	1	34	10	24	78.57
Grimsby Town	21	13	3	5	21	4	5	12	42	17	8	17	73	80	–7	40.48
Huddersfield Town	23	13	9	1	23	7	7	9	46	20	16	10	85	64	21	43.48
Hull City	13	11	2	0	13	6	3	4	26	17	5	4	52	24	28	65.38
Ipswich Town †	25	16	4	5	25	8	5	12	50	24	9	17	80	61	19	48.00
Leeds City ‡	1	0	0	1	1	1	0	0	2	1	0	1	3	4	–1	50.00
Leeds United	50	23	18	9	50	19	16	15	100	42	34	24	149	109	40	42.00
Leicester City †	65	43	15	7	65	22	16	27	130	65	31	34	257	172	85	50.00
Leyton Orient	6	3	3	0	6	3	1	2	12	6	4	2	18	8	10	50.00
Lincoln City	15	11	3	1	15	4	1	10	30	15	4	11	62	42	20	50.00
Liverpool †	92	44	29	19	91	25	23	43	183	69	52	62	244	250	–6	37.7
Loughborough ‡	5	5	0	0	5	2	2	1	10	7	2	1	29	7	22	70.00
Long Eaton Rangers ‡	1	1	0	0	1	1	0	0	2	2	0	0	6	1	5	100.00
Luton Town	20	19	0	1	20	10	7	3	40	29	7	4	91	27	64	72.5
Manchester City †	85	35	27	23	85	31	25	29	170	66	52	52	239	240	–1	38.82
Middlesbrough	52	31	10	11	52	22	12	18	104	53	22	29	186	152	34	50.96
Millwall	6	5	1	0	6	3	2	1	12	8	3	1	28	7	21	66.67
Nelson	1	0	0	1	1	1	0	0	2	1	0	1	2	1	1	50.00
New Brighton Tower ‡	3	2	0	1	3	2	0	1	6	4	0	2	11	6	5	66.67
Newcastle United †	84	52	22	10	84	31	19	34	168	83	41	44	319	238	81	49.4
Northampton Town	1	1	0	0	1	0	1	0	2	1	1	0	7	3	4	50.00
Norwich City	31	21	6	4	31	17	6	8	62	38	12	12	110	51	59	61.29
Nottingham Forest †	50	30	11	9	50	17	12	21	100	47	23	30	182	130	52	47
Notts County	24	11	9	4	24	9	5	10	48	20	14	14	74	60	14	41.67
Oldham Athletic	18	11	3	4	18	6	6	6	36	17	9	10	74	45	29	47.22
Oxford United	4	4	0	0	4	2	0	2	8	6	0	2	18	7	11	75.00
Plymouth Argyle	6	4	1	1	6	2	1	3	12	6	2	4	20	20	0	50.00
Port Vale	18	16	1	1	18	5	4	9	36	21	5	10	76	37	39	58.33
Portsmouth	29	20	3	6	29	8	10	11	58	28	13	17	91	60	31	48.28
Preston North End	33	15	11	7	33	11	9	13	66	26	20	20	107	90	17	39.39
Queens Park Rangers	22	18	3	1	22	10	7	5	44	28	10	6	82	42	40	63.64
Reading	3	2	1	0	3	2	1	0	6	4	2	0	11	6	5	66.67
Rotherham Town ‡	2	2	0	0	2	1	0	1	4	3	0	1	10	6	4	75.00
Rotherham County ‡	1	1	0	0	1	0	1	0	2	1	1	0	4	1	3	50.00
Sheffield United	47	29	6	12	47	15	10	22	94	44	16	34	161	135	26	46.81
Sheffield Wednesday	59	37	15	7	59	15	12	32	118	52	27	39	197	161	36	44.07
South Shields ‡	3	2	1	0	3	2	0	1	6	4	1	1	10	3	7	66.67
Southampton †	56	34	13	9	57	23	18	16	113	57	31	25	196	124	72	50.44
Stockport County	9	7	2	0	9	2	0	7	18	9	2	7	29	18	11	50.00
Stoke City	45	26	14	5	45	13	15	17	90	39	29	22	145	106	39	43.33
Sunderland	64	38	14	12	64	22	15	27	128	60	29	39	220	183	37	46.88
Sunderland Albion ‡	2	1	0	1	2	0	0	2	4	1	0	3	6	10	–4	25.00
Swansea City	15	11	3	1	15	4	3	8	30	15	6	9	51	32	19	50.00
Swindon Town	1	1	0	0	1	0	1	0	2	1	1	0	6	4	2	50.00
Tottenham Hotspur †	88	58	15	15	87	28	30	29	175	86	45	44	281	225	56	49.14
Walsall	9	7	2	0	9	3	3	3	18	10	5	3	46	19	27	55.56
Watford	14	11	3	0	14	7	2	5	28	18	5	5	49	29	20	64.29
West Bromwich Albion	63	33	16	14	63	22	14	27	126	55	30	41	225	184	41	43.65
West Ham United †	68	47	9	12	69	18	20	31	137	65	29	43	247	170	77	47.45
Wigan Athletic	8	8	0	0	8	7	0	1	16	15	0	1	50	5	45	93.75
Wimbledon ‡	14	9	3	2	14	7	4	3	28	16	7	5	51	26	25	57.14
Wolverhampton Wanderers †	50	33	7	10	50	16	10	24	100	49	17	34	167	139	28	49
York City	1	1	0	0	1	1	0	0	2	2	0	0	3	1	2	100.00

As of match played on 27 October 2024

Manchester United F.C. overall league record by competition

Competition	Home				Away				Total							Win%	Ref(s)
	Pld	W	D	L	Pld	W	D	L	Pld	W	D	L	GF	GA	GD
Premier League	618	429	116	73	619	318	155	146	1,237	747	271	219	2,308	1,178	1,130	60.39
Football League First Division	1,370	758	339	273	1,370	404	365	601	2,740	1,162	704	874	4,523	3,875	648	42.41
Football League Second Division	408	278	71	59	408	128	97	183	816	406	168	242	1,433	966	467	49.75
Football Alliance	33	19	7	7	33	9	5	19	66	28	12	26	146	132	14	42.42
Total	2,429	1,484	533	412	2,430	859	622	949	4,859	2,343	1,155	1,361	8,410	6,151	2,259	48.22