Mardela Middle and High School (MMHS) is a seven-year public middle school and high school in Mardela Springs, Wicomico County, Maryland, United States. It is the only combination middle and high school in Wicomico County Public Schools.

The school is located on the Eastern Shore of Maryland in the town of Mardela Springs in Wicomico County. The school is on Maryland Route 54, east of Maryland Route 313 and just north of U.S. 50. Mardela Springs is between the Eastern Shore towns of Vienna and Hebron.

The current school building was constructed between 1978 and 1980, on the same site as the previous school, which was built in 1937. The current building has 118,993 square feet (11,054.8 m) of space and is located on 50.56 acres (20.46 ha) of land.

Athletic programs offered at the school include the following:

• Fall: cheerleading, cross country, golf, boys' soccer, girls' soccer, and tennis
• Winter: boys' basketball, girls' basketball, cheerleading, indoor track & field, strength & conditioning, and wrestling
• Spring: baseball and softball

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  Mardela Springs Middle High School
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  Mardela Middle High School sign

• Tia Jackson (1990), former WNBA player and coach for the Duke Blue Devils
• Brian Hollamon (1991), former baseball coach for the Maryland Eastern Shore Hawks

• Wicomico County Public Schools
• List of high schools in Maryland

• Mardela Middle & High School website
• Map of school from Google Maps