Marghtumayn (Tajik: Марғтумайн or Махтамайн Makhtamayn, Yaghnobi Марғтумайн) is a village in Sughd Region, northwestern Tajikistan. It is part of the jamoat Anzob in the Ayni District, and located east of the village Anzob. Its population was 12 in 2007.