The Marysville Historic Commercial District, in Marysville, California, is a 23-acre (9.3 ha) historic district which was listed on the National Register of Historic Places in 1999.

The district included 59 contributing buildings and 27 non-contributing ones, on parts of 14 blocks. It is roughly bounded by First, Sixth, C, and E Streets.

It includes Mission/Spanish Revival and Italianate architecture.