McCook is an unincorporated community in Hidalgo County, Texas, United States. The community is located on Farm to Market Road 681, 30 miles (48 km) northwest of McAllen.

McCook was founded circa 1925. By 1936, the community had its own school district, post office, and church; for the next few decades, its population hovered near 40 residents. By 1964, the population had risen to 100. As of 2000, the population was 91; the residents were spread out over a rural area.