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Melissa Independent School District is a public school district based in Melissa, Texas (USA).

In addition to Melissa, the district serves a small portion of Weston and McKinney.

In 2009, the school district was rated "recognized" by the Texas Education Agency.

Schools

Melissa ISD has eight academic campuses:

Melissa High School (Grades 9-12)
Melissa Middle School (Grades 7-8)
Sixth Grade Center (Grade 6)
Harry McKillop Elementary School (Grades K-5)
North Creek Elementary School (Grades K-5)
Willow Wood Elementary School (Grades K-5)
Sumeer Elementary School (Grades K-5)
Melissa Ridge Education Center (Grades Pre-K, Early Childhood Special Education & Employee Daycare)

^ "2009 Accountability Rating System". Texas Education Agency. Archived from the original on October 25, 2015.

Public high schools

Allen ISD

Senior high schools (11–12)	Plano Senior Plano East Plano West
High schools (9–10)	Clark Jasper McMillen Shepton Vines Williams
Alternative schools (9–12)	PISD Academy

Senior high schools (11–12)	Princeton High
High schools (9–10)	Lovelady

Private high schools

Secular

Religious

Closed	Canyon Creek Christian Academy

This list may be incomplete.
Portions of some school districts extend into other counties, and other school districts (Bland ISD, Gunter ISD, Leonard ISD, Rockwall ISD, Royse City ISD, Trenton ISD, Van Alstyne ISD, Whitewright ISD) serve Collin County but have no high schools in it.
Westminster ISD was disestablished in 1989.