Memorial Square is a neighborhood located in Springfield, Massachusetts.

A predominantly Puerto Rican neighborhood with several parks, Memorial Square is within walking distance of Springfield's three nationally ranked hospitals, Baystate Medical Center, Shriner's Children's Hospital, and Mercy Medical.

Always a neighborhood of immigrants, Memorial Square was a primarily Greek neighborhood from the Industrial Revolution until the Great Latino Immigration of the 1980s to the present. The architecturally brilliant St. George's Greek Orthodox Cathedral, founded in 1907 and built in 1940, is a testament to Memorial Square's past as a vibrant Greek enclave.

A portion of the neighborhood was listed on the National Register of Historic Places in 1977 as the Memorial Square District.