Mission Rock station is a light rail station on the Muni Metro T Third Street line, located in the median of Third Street at Mission Rock Street in the Mission Bay neighborhood of San Francisco, California. The station opened with the T Third Street line on January 13, 2007. It has two side platforms; the northbound platform is north of Mission Rock Street, and the southbound platform south of Mission Rock Street, which allows trains to pass through the intersection before stopping at the station.

The stop is also served by the route 22 bus, plus the T Bus and 91 Owl bus routes, which provide service along the T Third Street line during the early morning and late night hours respectively when trains do not operate.