Mississippi Highway 76 (MS 76) is an east-west state highway in Itawamba County, Mississippi. It is a section of Mississippi's portion of Corridor V of the Appalachian Development Highway System. It branches off northeast from MS 25 northeast of Fulton and passes through the northeast quadrant of rural Itawamba County before connecting with Alabama's SR 24 section at the state line, just barely outside the city limits of Red Bay, Alabama.

MS 76 was proposed as a four-lane connection for SR 24 (and all of northeast Alabama) to Fulton, Tupelo, and I-22. Before April 11, 2023, it only extended 2.4 miles (3.9 km) from the state line to MS 23. The remaining 8.3-mile (13.4 km) stretch from MS 23 to MS 25 opened on that day, and was the final segment on Corridor V to open, making the trip between I-55 in Batesville to I-24 west of Chattanooga, Tennessee entirely a four-lane divided highway.

Route description

MS 76 begins at a T-intersection with MS 25 approximately 7 miles (11 km) from that highway's interchange with I-22/US 78 (Exit 108), and 9 miles (14 km) northeast of Fulton, in rural northeastern Itawamba County. It heads east as a four-lane divided highway with a grassy median without outside shoulders and follows an entirely new right-of-way. However, it roughly follows the path of Fairview Banner Road. After heading northeast for 8.3 miles (13.4 km), it then has a T-intersection with MS 23 7 miles (11 km) southeast of Belmont. The highway travels through wooded, hilly terrain, passing by some farms and crossing some small creeks before continuing into Franklin County, Alabama as SR 24.

History

Mississippi Highway 76
Location	Pontotoc
Length	9.1 mi (14.6 km)
Existed	1996–2014

The MS 76 designation originated as a temporary designation for the 9.1-mile-long (14.6 km) western portion of the MS 6/US 278 Pontotoc bypass (also known as the Pontotoc Parkway) in Pontotoc, more specifically the section between MS 6/US 278 and the interchange at MS 9. It existed between 1996, and the designation was dropped when the rest of the highway was finished to Tupelo at US 45 in 2014. It, too, was a four-lane divided highway and is also a section of Corridor V. The 5.8-mile-long (9.3 km) section between MS 6/US 278 on the west side of town to MS 15 was the first to open, with a 3.3-mile-long (5.3 km) extension to MS 9 opening in 1998. This MS 76 designation remained unsigned until the year 2000. The current MS 76 was opened in 2013 alongside the opening of SR 24's Red Bay, Alabama bypass.

Construction on the 8.3 miles (13.4 km) segment between MS 23 and MS 25 was originally scheduled to start in 2011 but was delayed due to funding concerns. The project was expected to be completed by the end of 2023, and it ultimately opened to traffic on April 11, 2023.

Major intersections

The entire route is in Itawamba County.

Location	mi	km	Destinations	Notes
​	0.0	0.0	MS 25 to I-22 / US 78 – Fulton, Belmont	Western terminus; segment between here and MS 23 opened to traffic on April 11, 2023, Corridor V follows SR 25 south
​	8.3	13.4	MS 23 to I-22 / US 78 – Tremont, Red Bay	Former western terminus until April 11, 2023
​	10.7	17.2	SR 24 east – Russellville	Alabama state line; eastern terminus; Corridor V follows SR 24 east
1.000 mi = 1.609 km; 1.000 km = 0.621 mi