Route 113 is a highway in northwestern Missouri. Its northern terminus is at U.S. Route 136 in Burlington Junction; its southern terminus is at U.S. Route 59 east of Mound City.

Beginning at the southern terminus with US 59 in Holt County, the highway travels approximately five miles east and curves northward at its intersection with Route B. Continuing north, the highway travels north five miles then intersects with Route A and C, where Maitland lies just east. Continuing another four miles the highway crosses into Nodaway County, and an additional mile later the road curves northeast where the highway crosses the Nodaway River.

Immediately after, it reverts to north and comes into Skidmore where it junctions with Route D at the town center. After a right turn at the stop sign, the highway travels east through the town and curves northward again after exiting, where it intersects with Route V. Thereafter, it crosses Florida Creek after two miles, then another two it intersects with Missouri Route 46. Then it travels north-northwest almost three miles until it passes through the sleepy hamlet of Quitman. After a large sweeping right and then left curve, the highway continues north about 3.5 miles to its northern terminus in Burlington Junction with US 136.

County	Location	mi	km	Destinations	Notes
Holt	Hickory Township	0.000	0.000	US 59 – Mound City, Oregon
Nodaway	Green Township	18.053	29.053	Route 46 to US 59 – Maryville
	Burlington Junction	26.216	42.191	US 136 to US 71 – Tarkio
1.000 mi = 1.609 km; 1.000 km = 0.621 mi