Route 350 is a highway in the Kansas City, Missouri, area. Its eastern terminus is at the Interstate 470/U.S. Route 50 (I-470/US 50) interchange in Lee's Summit; its western terminus is at I-435 in Kansas City. Along the northern terminus, it fades into Blue Parkway and part of the route is an old alignment of US 50. Notable development along Route 350, particularly in and nearing Raytown, occurred in the late 1970s into the 1980s. However, much of this area now shows its age and the changing socioeconomic makeup of the area, with retail chains falling into disrepair or closing.

The entire route is in Jackson County.

Location	mi	km	Destinations	Notes
Kansas City	0.000	0.000	55th Street Blue Parkway	Continues as Blue Parkway
	0.349– 0.669	0.562– 1.077	I-435	I-435 south exit 66, north exit 66B.
	1.310	2.108	63rd Street – Raytown	Interchange
Raytown	2.081	3.349	Blue Ridge Boulevard	Eastbound exit and westbound entrance only
Kansas City	5.915	9.519	Route V (Noland Road)
Unity Village	7.843	12.622	Colbern Road, Bannister Road	Blue Parkway designation exits the highway
Lee's Summit	8.533– 8.872	13.733– 14.278	I-470 / US 50 west – Wichita, St. Louis US 50 east – Sedalia	Road continues as US 50 eastbound
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Incomplete access       Route transition