Route 413 is a highway in Missouri running between Route 13 in Springfield and Route 13 in Reeds Spring. It is an older alignment of Route 13 which was later rerouted. Except for two sections (in Springfield between Route 13 and US 60 and a 4-mile segment between US 60 and Route 265 southwest of Billings), the road runs concurrent with other designations for its entire length.

Route 413 begins at an intersection with Route 13, Route 76 and Route 265 in Branson West. Route 265 joins up with 413 at the southern terminus and the two routes are concurrent. The roads head north and intersect with local roads. Routes 76 and 13 parallel Routes 413 and 265 as the roads continue out of Branson West. The routes proceed through a mountainous region and enter Reeds Spring, where they intersect with a now-separated Route 76. Routes 413 and 265 pass to the west of Emerson Airport and continue northward, still paralleling Route 13.

Routes 413 and 265 turn sharply to the west and intersect with Route 248. Route 248 joins the concurrency and the three roads make several changes in direction before steadily heading north. Routes 413, 265, and 248 begin to turn in different directions again and cross through more rural territory. The three roads go through a dense forest just south of Galena. At the intersection with Route 176, the three routes turn to the west, where Route 248 turns off. Routes 413 and 265 continue farther west. Northwest of Galena, the roads intersect with their first supplemental route, Route AA. Routes 413 and 265 head through farmlands, where Route 173 terminates.

The roads intersect with another county road in Elsey as they continue northward. Routes 265 and 413 pass a dense forest to the north and heads into Crane. The routes leave Crane after intersecting with a few county and local roads. Near Logan, Route 265 turns off to the east and Route 413 continues northward. Route 413 intersects and becomes concurrent with U.S. Route 60. Routes 413 and 60 then enter the Republic city limits. Route 174 intersects soon afterward. 413 and 60 split and Route 413 heads northeast into Springfield, where Route 413 comes to an end at Route 13.

The highway was originally commissioned in 2000 to replace a section of Route 13 that was rerouted along the James River Freeway and only ran from Kansas Expressway in Springfield to the James River Freeway.

County	Location	mi	km	Destinations	Notes
Stone	Branson West	0.000	0.000	Route 13 / Route 76 / Route 265 south	South end of Route 265 overlap
	Reeds Spring	1.950	3.138	Route 76
		3.557	5.724	Route 248 east	South end of Route 248 overlap
	Galena	11.131	17.914	Route 176
		11.515	18.532	Route 248 west	North end of Route 248 overlap
	Elsey	16.551	26.636	Route 173
Stone–Christian county line	​	27.523	44.294	Route 265 north	North end of Route 265 overlap
Christian	​	31.439	50.596	US 60 west	South end of US 60 overlap
	Billings	32.400	52.143	Route 14
Greene	Republic	39.594	63.720	Route 174
		43.749	70.407	US 60 east / Route 360 west	North end of US 60 overlap
	Springfield	46.923	75.515	US 160
		48.745	78.447	Route 13 (Kansas Expressway)
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus