Monte Grande is an unincorporated community in Cameron County, Texas, United States. According to the Handbook of Texas, the community had a population of 97 in 2000. It is located within the Rio Grande Valley and the Brownsville-Harlingen metropolitan area.

Monte Grande existed as a community in the late 1970s. The county highway map of that decade showed one business here. Its population was 97 in 2000.

Monte Grande is located off Farm to Market Road 2925, 12 miles (19 km) northeast of Harlingen in northern Cameron County.

Today, the community is served by the Los Fresnos Consolidated Independent School District. Children in the community attend Las Yescas Elementary School, Liberty Memorial Middle School, and Los Fresnos High School.