Moonshine is an unincorporated community and census-designated place in St. James Parish, Louisiana, United States. It was first listed in the 2010 census with a population was 194. The community is located on the west bank of the Mississippi River.

According to the U.S. Census Bureau, the community has an area of 0.430 square miles (1.11 km); 0.364 square miles (0.94 km) of its area is land, and 0.066 square miles (0.17 km) is water.

Historical population

Census	Pop.	Note	%±
2010	194		—
2020	168		−13.4%
U.S. Decennial Census

Moonshine CDP, Louisiana – Racial and ethnic composition
Note: the US Census treats Hispanic/Latino as an ethnic category. This table excludes Latinos from the racial categories and assigns them to a separate category. Hispanics/Latinos may be of any race.

Race / Ethnicity (NH = Non-Hispanic)	Pop 2010	Pop 2020	% 2010	% 2020
White alone (NH)	15	8	7.73%	4.76%
Black or African American alone (NH)	165	144	85.05%	85.71%
Native American or Alaska Native alone (NH)	0	0	0.00%	0.00%
Asian alone (NH)	0	0	0.00%	0.00%
Pacific Islander alone (NH)	0	0	0.00%	0.00%
Some Other Race alone (NH)	0	0	0.00%	0.00%
Mixed Race or Multi-Racial (NH)	1	10	0.52%	5.95%
Hispanic or Latino (any race)	13	6	6.70%	3.57%
Total	194	168	100.00%	100.00%

In 2020, its population was 168, down from 194 in 2010.