Moyen-Ogooué is one of Gabon's nine provinces. It covers an area of 18,535 km (7,156 sq mi). The provincial capital is Lambaréné. As of 2013, 69,287 people lived there.

Unlike any other province of Gabon, Moyen-Ogooué has neither seacoast nor a foreign border. It borders the following provinces:

• Estuaire Province – northwest
• Woleu-Ntem Province – north-northeast
• Ogooué-Ivindo Province – east
• Ogooué-Lolo Province – southeast, at a quadripoint
• Ngounié Province – south
• Ogooué-Maritime Province – west-southwest

Moyen-Ogooué borders all but two of the rest of Gabon's provinces, thus more than any other province.

Moyen-Ogooué is divided into 2 departments:

• Abanga-Bigne Department (capital Ndjolé)
• Ogooué et des Lacs Department (capital Lambaréné)

• Petringa, Maria. Brazza, A Life for Africa. Bloomington, IN: AuthorHouse, 2006. ISBN 978-1-4259-1198-0. Describes Pierre Savorgnan de Brazza's extensive explorations of the Ogoué River basin.