Muikamachi Station (六日町駅, Muikamachi-eki) is a railway station located in the city of Minamiuonuma, Niigata, Japan, operated jointly by the East Japan Railway Company (JR East) and the third sector Hokuetsu Express.

Muikamachi Station is a station on the Jōetsu Line, and is located 111.8 kilometers from the starting point of the line at Takasaki. It is also a terminal station for the Hokuhoku Line, although trains continue on to Echigo-Yuzawa via the Joetsu Line.

The station has a single side platform and two island platforms serving five tracks. The station has a Midori no Madoguchi staffed ticket office.

1	■ Jōetsu Line	for Echigo-Yuzawa and Minakami
2	■ Jōetsu Line	(siding)
3	■ Jōetsu Line	for Nagaoka and Niigata
4	■ Hokuhoku Line	for Echigo-Yuzawa
5	■ Hokuhoku Line	for Tōkamachi and Naoetsu

Muikamachi Station opened on 18 November 1923. Upon the privatization of the Japanese National Railways (JNR) on 1 April 1987, it came under the control of JR East.

In fiscal 2017, the station was used by an average of 1794 passengers daily (boarding passengers only).

• Muikamachi Post Office
• National Route 17

• List of railway stations in Japan

• Media related to Muikamachi Station at Wikimedia Commons
• JR East Muikamachi Station (in Japanese)
• Hokuetsu Express Station information (in Japanese)