The Municipality of Destrnik (pronounced [ˈdeːstəɾnik]; Slovene: Občina Destrnik) is a municipality in northeastern Slovenia. The seat of the municipality is the settlement of Destrnik. It lies in the Slovene Hills (Slovene: Slovenske gorice) north of Ptuj. The area is part of the traditional region of Styria. It is now included in the Drava Statistical Region.

In addition to the municipal seat of Destrnik, the municipality also includes the following settlements:

• Media related to Municipality of Destrnik at Wikimedia Commons
• Municipality of Destrnik on Geopedia
• Destrnik municipal site