Museu Lasar Segall (in English: Lasar Segall Museum) is an art museum in São Paulo, Brazil.

Designed in 1932 by architect Gregori Warchavchik, the building which houses the museum was the residence and art studio of Lithuanian Brazilian artist Lasar Segall until his death in 1957. Segall's family opened the museum in 1967 to showcase the work of the artist. The collection contains more than 3,000 items by Lasar Segall, including paintings, sculpture, drawings, and prints.

In 1985, the Museum was incorporated into the National Pro-Memory Foundation, now integrated into the Brazilian Institute of Museums (IBRAM) of the Ministry of Culture, as a special entity. In addition to its collection, the Museum is a center for cultural activities, offering programs of guided visits, courses in the areas of engraving, photography, literary creation, and cinema projection. It also houses a large library specialized in the performing arts and photography.The Museum, as a federal body, is supported by the Cultural Association of Friends of the Lasar Segall Museum (ACAMLS), a non-profit organization, made possible by the collaboration of public and private institutions, as well as individuals who work together with the Museum.

Museu Lasar Segall is located at 111 Rua Berta in the Vila Mariana district of São Paulo and is operated by a non-profit foundation.

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