Myrtle Beach has been separated from the continental United States since 1936 by the Intracoastal Waterway, forcing the city and area in general to develop within a small distance from the coast. In part due to this separation, the area directly northwest of Myrtle Beach, across the waterway, remained primarily rural for a while, whereas its northeastern and southwestern ends were bordered by other developed tourist towns, North Myrtle Beach and Surfside Beach. Since then, the inland portion of the Myrtle Beach area has developed dramatically.

Myrtle Beach is 67 miles (108 km) by highway southeast of Florence, South Carolina, 94 miles (151 km) northeast of Charleston, South Carolina, and 74 miles (119 km) southwest of Wilmington, North Carolina.

According to the United States Census Bureau, the city has a total area of 23.69 square miles (61.4 km), of which 23.42 square miles (60.7 km) is land and 0.27 square miles (0.70 km) (1.14%) is water.

According to the Köppen climate classification, Myrtle Beach has a humid subtropical climate or Cfa – typical of the Gulf and South Atlantic states. The city enjoys abundant sunshine year-round with more than 2800 hours annually.

The summer season is long, hot, and humid in Myrtle Beach. Average daytime highs are from 83 to 91 °F (28 to 33 °C) and average night-time lows are near 70 °F (21 °C). The coastal location of Myrtle Beach mitigates daytime summer heat somewhat compared to inland areas of South Carolina: Thus, while nearby Florence averages 65 days annually with high temperatures of 90 °F (32 °C) or higher – Myrtle Beach averages only 21. The Bermuda High pumps in humidity from the tropical Atlantic toward Myrtle Beach, giving summers a near-tropical feel in the city. The warm Atlantic Ocean reaches 80 °F (27 °C) or higher in the summer months off Myrtle Beach, making for warm and sultry summer nights. Summer thunderstorms are common in the hot season in Myrtle Beach, and the summer months from June through September have the most precipitation. In summer, thunderstorms normally build during the heat of the day – followed by brief and intense downpours. On average, September is the wettest month, with August close behind, due to the combination of thunderstorms and tropical weather systems that peaks these months.

Myrtle Beach has mostly mild winters of short duration: Average daytime highs range from 57 to 61 °F (14 to 16 °C) and nighttime lows are in the 36 to 38 °F (2 to 3 °C) from December through February. Winter temperatures vary more than summer temperatures in Myrtle Beach: Some winters can see several cold days with highs only in the upper 40s F (7–9 °C), while other winter days can see highs in the upper 60s and low 70s F (19–23 °C). Myrtle Beach averages 33 days annually with frost, though in some years less than 15 days will see frost. Snowfall is very rare in Myrtle Beach; however, at least a trace of snow falls a few times each decade. In February 2010, a rare 2.8 inches (71 mm) of snow fell in Myrtle Beach. The spring (March, April and May) and fall (September, October and November) months are normally mild and sunny in Myrtle Beach, with high temperatures in the 60s and 70s. The beach season in Myrtle Beach normally runs from late April through late October. Sea surface temperatures are often in the lower 80's (26–28 °C) off South Carolina in summer and early fall.

The temperature range measured in Myrtle Beach has historically ranged from a record high of 104 °F (40 °C) on June 26, 1952 and August 5, 1954 to the record winter cold of 9 °F (−13 °C) on February 18, 1958. In spite of the mild winter averages, ice days have been recorded, albeit rarely. The coldest daily maximum was 25 °F (−4 °C) in January 11, 1962 whereas the normal year between 1991 and 2020 had the coldest maximum average of 37 °F (3 °C). Overnight lows can be extremely hot and muggy, although the record warm low of 88 °F (31 °C) on July 12, 1942 is some way above the means of 81 °F (27 °C) for the warmest annual minimum.

Summer thunderstorms are typically brief, but severe thunderstorms do occur on occasion. Tornadoes are rare, with the most significant event occurring in 2001 when multiple tornadoes touched down in the area. Tropical cyclones occasionally impact Myrtle Beach, though weaker tropical storms and weak tropical lows are more common. Like most areas prone to tropical cyclones, a direct hit by a major hurricane is infrequent in Myrtle Beach. The last hurricane to cause significant damage in Myrtle Beach was Hurricane Hugo in 1989. The worst hurricane in Myrtle Beach's history was Hurricane Hazel in 1954.

Myrtle Beach is the largest principal city of the Myrtle Beach-Conway, SC Combined Statistical Area, which had an estimated population of 463,209 in 2023, and includes the Myrtle Beach-Conway-North Myrtle Beach, SC Metropolitan Statistical Area (Horry County) and the Murrells Inlet, SC Micropolitan Statistical Area (Georgetown County).

As of the 2020 census, there were 35,682 people, 13,817 households, and 7,678 families residing in the city.

At the 2010 census, the population of Myrtle Beach was 27,109. At the 2000 census, there were 22,759 permanent residents in Myrtle Beach, 10,413 households, 5,414 families, 1,356.5 per square mile (523.7/km), with 14,658 housing units at an average density of 873.5 per square mile (337.3/km).

The city's racial makeup was:

• 72.3% White
• 13.9% Black
• 0.7% Native American
• 1.5% Asian
• 0.3% Pacific Islander
• 8.7% from other races
• 2.7% from two or more races.

Hispanic or Latino residents, of any race, were 13.7% of the population.

Of the total Myrtle Beach population:

• 18.0% were 1–17
• 11.0% were between 18 and 24
• 33.6% were between 25 and 44
• 22.5% were between 45 and 64
• 15.0% were 65 or older
• Median age was 37 years
• 103 males per 100 females overall
• 101 males per 100 females age 18 and over

• Overall median income for a household in the city was $50,173
• Median income for a family was $43,900
• Males had a median income of $26,039
• Females had a median income of $22,473
• The per capita income for the city was $23,214.
• About 7.6% of families and 12.0% of the population were below the poverty line, including 17.1% of those under age 18 and 6.6% of those age 65 or over.

Crime rate levels in Myrtle Beach are high compared to the rest of South Carolina. The FBI reported 583 cases of violent crime in the year 2016, of which 5 were murder, 46 were rape and 139 were robbery. Aggravated assault 348, property crime 4395, burglary 469, larceny theft 3555, motor vehicle theft 371, and arson 10 were also reported.

The average number of crimes per thousand population is 0.16 murders, 1.43 rapes, 4.31 robberies and 10.83 assaults.

The FBI reported 483 violent crimes in 2000, of which 1 was murder and 39 were rapes.

Myrtle Beach's economy is dominated by the tourist industry; hotels, motels, resorts, restaurants, attractions, and retail developments exist in abundance to serve visitors.

Hosting over 20 million visitors annually, the Grand Strand is home to an array of tourist attractions, and the area receives a large influx of visitors during all seasons. It is estimated that nearly 100,000 visitors a year are international travelers, including tourists from Canada, Germany and the United Kingdom.

Myrtle Beach hosts a variety of special conventions, events, and musical concerts. The area's attractions include its beaches and courses, amusement parks, an aquarium, Legends in Concert, retail developments, shopping complexes and over 1,900 restaurants including seafood restaurants. The area also has dinner theaters, nightclubs, and many tourist shops. Myrtle Beach has approximately 425 hotels, with many on the beachfront, and approximately 157 accommodation units in total. The area is also home to over 80 golf courses and over 30 miniature golf courses.

Live shows are offered year round at theaters including the Alabama Theatre, Carolina Opry, Asher Theater, Calvin Gilmore Theater, Legends in Concert, and Medieval Times Family Dinner Theater. Several shows offer special holiday themed shows.

The Myrtle Beach Boardwalk opened in 2010 and has been recognized as the nation's #3 boardwalk by National Geographic and one of the best US boardwalks by Travel + Leisure magazine. The Myrtle Beach Skywheel opened at the boardwalk in May 2011, and is a 200-foot (61 m) observation wheel, similar to a ferris wheel, with glass gondolas that look over the Atlantic Ocean. This is the first wheel of its kind in the U.S. Myrtle Beach State Park, established in 1935, has just under a mile of Grand Strand beach and is a prime location for camping, swimming, hiking, biking, and fishing. Pier 14 by the Boardwalk.

The Myrtle Beach Convention Center is a large facility that hosts a variety of meetings, conferences, exhibits, and special events every year. The expansive center, which opened in 2003, has a Sheraton hotel and resort.

Each March since 1951 during Ontario's spring break, Myrtle Beach has hosted Canadian-American Days, also known as Can-Am Days. Tens of thousands of tourists flock to the area for a week's worth of special events. Myrtle Beach is also home to Coastal Uncorked, a food and wine festival held in the late spring annually. The city hosts Sun Fun Festival early each June. Later in June, Myrtle Beach is a popular destination for recently graduated high school seniors for Senior Week.

Carolina Country Music Fest (CCMF) is an outdoor country music festival that takes place in June of each year and was founded in 2015 by Charlotte-based company Full House Productions. Due to concerns surrounding the coronavirus pandemic the festival wasn't held in 2020, but is scheduled to return in 2021 and take place on 10–13 June 2021.

Myrtle Beach International Airport serves the city and surrounding area. With regular flights to and from destinations such as Atlanta, Boston, Detroit, Fort Lauderdale, New York and Washington, the airport is well connected for both domestic and international tourists. It also serves as a seasonal gateway to and from the likes of Chicago, Dallas and Toronto.

The city is between Wilmington, North Carolina and Charleston, South Carolina with U.S. Route 17 serving as the main transport link for those journeying between those cities.

Thongs (or any swimwear revealing any portion of the buttocks) are not permitted in public in Myrtle Beach, including all beaches. Violators of the ban may be arrested, jailed, or fined. The city's "thong ordinance" has been in effect since the 1990s.

Myrtle Beach Bike Week, also called "Harley Bike Week", is a week-long motorcycle rally first held in 1940, the same year Kings Highway was paved. The event has attracted as many as 200,000 visitors to the city every May. Black Bike Week, founded in 1980, takes place the weekend around Memorial Day Weekend and is the largest African American motorcycle rally in the US and attracts as many as 400,000 visitors. The event was created in response to a history of discrimination against African-American visitors and riders to Myrtle Beach and the Grand Strand Area.

The Myrtle Beach government created 15 new laws aimed at preventing all sanctioned motorcycle events within the city in response to controversy including accusations of racism by African-American riders during their event and complaints of lawlessness and poor behavior during all highly attended events. Several lawsuits by the National Association for the Advancement of Colored People (NAACP) against Myrtle Beach businesses were settled with agreements that discrimination cease, compensation be given to some plaintiffs, and employees be given diversity training. The NAACP suit against the City of Myrtle Beach was settled in 2006 without the city paying damages, but with the agreement police would use the same traffic control rules during both the black and the white motorcycle rallies.

The South Carolina Supreme Court in June 2010 unanimously overturned one of the 15 ordinances, which had required all motorcyclists to wear helmets, on the grounds that the state law, requiring helmets only for riders under age 21, cannot be preempted by a city ordinance. In addition, the Court ruled that the ordinance created undue confusion, and that the city itself had invalidated their own helmet law and some other ordinances in a subsequent amendment. The law had been challenged by a group of motorcyclists and a group of Myrtle Beach businesses called BOOST, Business Owners Organized to Support Tourism, who opposed the city's anti-motorcycle tourism policy.

Major shopping malls in Myrtle Beach include:

• Barefoot Landing is an outdoor shopping complex that consists of several divided sections on filled land over top of Louis Lake, next to the Intracoastal Waterway. It contains many stores and attractions such as House of Blues (opened in 1997) and the Alabama Theatre. Opened in 1988.
• Broadway at the Beach is a shopping complex set on 350 acres (1.4 km) along the U.S. 17 Bypass surrounding the 23-acre (9.3 ha) Lake Broadway. It is the largest festival entertainment complex in South Carolina.
• Coastal Grand Mall opened in 2004 and is the second largest indoor malls in the state. The mall, which has indoor and outdoor shopping areas, has a gross leasable area of 1,047,732 square feet (97,300 m). The single-story facility has five anchor stores (including Sears, Belk, JCPenney, and Dillard's), a 14-screen movie theater, a food court, and roughly 170 stores in total.
• The Market Common is a lifestyle district housing several upscale retail and apartments. It is on the site of the former Myrtle Beach Air Force Base.
• Myrtle Beach Mall is 525,385 square feet (48,800 m), and has three anchor stores, Bass Pro Shops, Belk and JCPenney. The single-story mall also has a 12-screen movie theater, a food court, and other specialty stores. It used to be known as Colonial Mall, and was built as Briarcliffe Mall.
• Tanger Outlets is a shopping outlet center. There are two locations, one near Briarcliffe Acres and one near Carolina Forest.

The area is home to numerous golf courses and mini-golf courses along the Grand Strand and further inland. Myrtle Beach has been called the "Golf Capital of the World" because of the roughly 100 golf courses there, the record 4.2 million rounds played, and many miniature golf courses. 3.2 million total rounds of golf were played in 2017, down a "few hundred rounds" from a decade earlier. The number of golf courses more than doubled to over 120 over a 20-year period before declining late in the first decade of the 21st century. Tiger Woods declared Myrtle Beach "the mecca of golf" when visiting in 1997. The majority of the area's golf courses are public. The Grand Strand is home of "Hootie and the Blowfish Day After the Masters Tournament". Extensive Chinese investment to the Myrtle Beach area golf market has resulted in a significant surge of Chinese tourists to the area and also resulted in 25+ golf courses being owned and/or operated by Chinese nationals.

Some of the notable golf courses and/or resorts include Barefoot Resort & Golf and TPC of Myrtle Beach.

From 1998 to 2009 and again starting in 2011 (no Saturday races were held in 2010 due to snow), the area hosted the Bi-Lo Myrtle Beach Marathon presented by Chick-Fil-A, every February featuring (since 2004) the Friday night Royal Bank of Canada 5K and the Saturday Dasani Half Marathon and Bi-Lo Marathon (from 1998 until 2008, a relay was held but dropped because of the popularity of the other events). Marathon day draws the limit of 6,000 runners annually (2,500 full, 3,500 half) and results usually in an unusual dawn as the race starts before dawn (6:30 am) in order to finish by 2:30 pm.

Myrtle Beach is home to the Myrtle Beach Pelicans, a Carolina League baseball team and a Chicago Cubs farm franchise. It was also home to the Myrtle Beach Mutiny, a pro soccer team playing in the Premier Development League until 2018.

Pelicans Ballpark is the home field of the Myrtle Beach Pelicans. It opened in 1999. It is the finish point of the Bi-Lo Myrtle Beach Marathon. Pelicans Ballpark is also home of the annual "Baseball at the Beach" collegiate baseball tournament. Hosted by Coastal Carolina University each year, the tournament pits participating NCAA Division I baseball programs in the United States.

NASCAR-sanctioned Stock car racing was held at Myrtle Beach Speedway, a .538-mile (866 m), semi-banked, asphalt-paved oval track lon US 501. Drivers in the Late Model classes will compete (against those of Greenville-Pickens Speedway) for the South Carolina Championship in the NASCAR Whelen All-American Series. South Carolina Champions' scores will be calculated against other state and provincial champions for a continental championship.

It hosted the 2010 UOA Nationals where 8 collegiate ultimate teams from 5 conferences will be represented.

The city of Myrtle Beach has a council-manager government. The Mayor sits as a Council member-at-large and presides over City council meetings. If the Mayor cannot preside over a City Council meeting, the Mayor Pro-Tem is the presiding officer of the meeting until such time as the Mayor returns to the seat. The City Manager is responsible for the administration and the day-to-day operation of all of the municipal services and city departments. The City Manager also maintains intergovernmental relationships with federal, state, county and other local governments. The city of Myrtle Beach reformed into a council-manager government system in 1974 under the administration of Mayor Bob Hirsch and city manager David Stradinger, who moved away from the city's former strong-mayor form of government.

Brenda Bethune is the mayor of Myrtle Beach. She has served since 2018.

Myrtle Beach is served by a single public school district. Horry County Schools educates around 40,000 students and is the third largest school district in South Carolina.

Below is a list of private schools and charter schools within or near the city of Myrtle Beach.

Myrtle Beach has the following college and post-secondary schools:

The Grand Strand and Florence, South Carolina, share a common defined market by Nielsen Media Research in Horry, Marion, Dillon, Darlington, Marlboro, Scotland, Robeson, and Florence counties. Two major stations are licensed to Myrtle Beach: NBC affiliate WMBF-TV 32 and Fox affiliate WFXB 43. Myrtle Beach is also served by PBS member stations WHMC/WJPM-TV 23/33, licensed respectively to Conway and Florence, and two commercial stations licensed to Florence: CBS affiliate WBTW 13 (with MyNetworkTV on DT2) and ABC affiliate WPDE-TV 15, (with The CW on 15.2). WBTW has moved most of its operations to Myrtle Beach, while WPDE is now based in Conway.

The Myrtle Beach area is served by the following full power FM radio stations:

Weather Radio Frequencies: 162.4, 162.5, 162.55
AM Radio Rrequencies: 900, 1050, 1200

The Sun News has traditionally been the largest daily paper published along the Grand Strand, with a readership base extending from Georgetown, South Carolina, to Sunset Beach, North Carolina. The paper has been in existence since the 1930s and was formerly published by Knight Ridder before that company was bought by The McClatchy Company. Like many newspapers, the paper has declined in recent years due to shifts in readership and financial pressures at its parent company. It stopped local printing operations and downsized its newsroom in May 2020.

Myrtle Beach is also served by The Myrtle Beach Herald, a weekly newspaper that is part of the Waccamaw Publishers group. The Herald also produces a newspaper targeted at tourists called Visit!.

In 2020, Charleston-based The Post and Courier set up an official bureau in Myrtle Beach, after years of attempting to move into the market and purchasing The Georgetown Times, which it merged with the new operation.

Grand Strand Medical Center (GSMC) is a 369-bed acute care hospital and Level 1 Adult Trauma Center known for its programs in cardiology, heart surgery, and stroke treatment. It was opened on 21 April 1978 to succeed the former Ocean View Memorial Hospital (1958-1978), the first major hospital in Myrtle Beach. GSMC contains the only cardiac surgery and neurosurgery programs in the greater Myrtle Beach area and was a recipient of the Healthgrades 100 Best Hospitals for Cardiac Surgery in 2012 and 2013. As a teaching hospital, Grand Strand Medical Center is the home of ACGME accredited residency training programs (internal medicine, general surgery, emergency medicine, and family medicine), and hosts rotating medical students from the University of South Carolina and Edward Via College of Osteopathic Medicine (VCOM). Over 270 physicians and 1,400 staff serve at the facility.

Myrtle Beach International Airport is a county-owned public-use airport three miles (4.8 km) southwest of the central business district of Myrtle Beach. It was formerly known as Myrtle Beach Jetport (1974–1989) and is on the site of the former Myrtle Beach Air Force Base. The 11,500-square-foot (1,070 m) general aviation terminal, opened in May 2010, is located on the opposite side of the airport on Airdrome Street, near The Market Common. The terminal replaced a building previously used as base operations for the Myrtle Beach Air Force Base.

The Waccamaw Coast Line Railroad is a 14.1-mile (22.7 km) short-line railroad division of the Baltimore and Annapolis Railroad, extending from a connection with the Carolina Southern Railroad, another division of that company, at Conway to Myrtle Beach. The line was opened in 1900 by the Conway Coast and Western Railroad, a predecessor of the Atlantic Coast Line Railroad. The Seaboard System Railroad sold the line to Horry County in November 1985, and it was operated by the Horry County Railway until October 1987, when the WCLR took over. The Carolina Southern Railroad acquired the WCLR in September 1995, and since then it has been a division of the Baltimore and Annapolis Railroad. Horry County owns the line but leased it to the Carolina Southern Railroad in 2000.

Carolina Southern Railroad is a short line rail operator running on less than 95 miles (153 km) of rail at a maximum speed of 10 mph (16 km/h). It transports mostly freight brought to it from national rail operators. The company makes one scheduled delivery per month into the City of Myrtle Beach. It is off of Main Street in Conway, South Carolina, and is one of the few remaining train depots in South Carolina. It has been painstakingly restored to its former glory and the Carolina Southern Railroad has become one of the frequent destinations for freight services as well as passenger cars and observational locomotives. The railroad was originally erected in late 1886 and the first train steamed into the Conway Depot in December 1887.

The Carolina Southern Railroad stands as a permanent landmark in Southern History. Carolina Southern Railroad is a member of the Carolina Rails system with connections that run from Whiteville, North Carolina, to Mullins, South Carolina, and also from Chadbourn, North Carolina, to Conway. Carolina Southern railroad is also responsible for operation of the Waccamaw Coast Line Railroad, which is a railway that runs from Conway to Myrtle Beach.

On August 30, 2011, Carolina Southern Railroad voluntary shut down because several bridges along the rail were overdue for maintenance. The shutdown caused Carolina Southern Railroad to lay off nearly all of its employees. On May 24, 2012, the Federal Railroad Administration (FRA) commenced a bridge inspection on the CSR and the Waccamaw Coastline Railroad (the Horry County portion of rail). Fifty-two of 187 bridges were inspected and seven had critical defects. On May 26, 2011, the CSR voluntarily ceased operation, so that they could bring in a certified bridge engineer to inspect the seven critical bridges and prepare a plan for their repairs. Based on the engineer's recommendations, CSR made the necessary repairs on the bridges and CSR resumed operations August 8, 2011. The FRA returned to inspect the bridges and made a recommendation that CSR cease operations until all bridge repairs were completed. There are efforts to bring the railroad back online.

In 2015, railroad operator RJ Corman acquired the former CSR line and re-opened it freight service in early April 2016.

Until 1955 the Atlantic Coast Line Railroad ran passenger rail service from the Myrtle Beach Station to Chadbourn, where a connection could be made to interstate ACL train service.

• Future I-73
• Future I-74
• US 17
• 
  US 17 Bus.
• US 501
• SC 31
• Farrow Parkway
• Grissom Parkway
• Harrelson Boulevard
• Ocean Boulevard

Within the last decade, new roads have been created to ease congestion caused by the yearly influx of visitors. Most of these roads follow the Metro Loop Road Plan, organized in 1997 to improve the traffic flow of Myrtle Beach. Some of the roads included have either been funded through Road Improvement Development Effort (RIDE I) funding or through the City of Myrtle Beach.

RIDE II plans include the third phase of S.C. Highway 31, a graded separation of Farrow Parkway and US 17 Bypass at the back gate of the former Air Force base, and many other projects. The county is debating where to allocate the $400 million generated through a proposed 1-cent sales tax. Other road projects in Horry County, including some in Aynor and Conway, will be included when voted upon.

Plans exist for Myrtle Beach to be served by two interstates, Interstate 73 and Interstate 74. The Robert Edge Parkway will connect I-74 to downtown North Myrtle Beach.

Myrtle Beach is served by the Coast RTA and the Pee Dee Regional Transportation Authority.

• Sigmund Abeles, American figurative artist
• Meher Baba, spiritual master who said he was the Avatar of the age and established the Meher Spiritual Center near Myrtle Beach. He remained silent from 1925 until his death in 1969.
• Steve Bailey, bassist
• Madison Iseman, actress
• Robert H. Brooks, founder of Naturally Fresh, Inc. and Hooters of America chains
• Dusty Button, ballet dancer
• Shane Carruth, filmmaker
• Brandon Frye, former NFL player, drafted by the Houston Texans
• Everett Golson, active CFL quarterback and starting quarterback for Notre Dame team that played in the 2013 BCS National Championship Game
• Anthony James, character actor in films and television
• Dustin Johnson, PGA Tour player (attended Coastal Carolina University)
• Ewa Laurance, professional billiards player
• Elliot Levine, keyboardist and member of Heatwave
• Clint Newton, rugby league player for the Penrith Panthers
• Nancy O'Dell, television Personality
• Hunter Renfrow, NFL wide receiver and return specialist for the Las Vegas Raiders
• Brian Rutenberg, American painter
• Ramon Sessions, NBA player for the Washington Wizards
• Kelly Wearstler, interior designer and judge on Bravo's Top Design

Myrtle Beach has five sister cities, as designated by Sister Cities International:

• Burlington, Ontario, Canada
• Keighley, West Yorkshire, United Kingdom
• Pinamar, Argentina
• Killarney, County Kerry, Ireland
• Tiberias, Israel

• List of municipalities in South Carolina

Wikimedia Commons has media related to Myrtle Beach, South Carolina.

Wikivoyage has a travel guide for Myrtle Beach.

• Geographic data related to Myrtle Beach, South Carolina at OpenStreetMap
• Official website