Nędzerzew [nɛnˈd͡zɛʐɛf] is a village in the administrative district of Gmina Opatówek, within Kalisz County, Greater Poland Voivodeship, in west-central Poland. It lies approximately 8 kilometres (5 mi) north-west of Opatówek, 4 km (2 mi) east of Kalisz, and 109 km (68 mi) south-east of the regional capital Poznań.