NGC 6541 (also known as Caldwell 78) is a globular cluster in the southern constellation of Corona Australis. It is estimated to be around 14 billion years old.

The globular cluster was discovered by Niccolò Cacciatore at the Palermo Astronomical Observatory, Sicily, on March 19, 1826. It was independently found by James Dunlop on July 3, 1826.

The cluster is relatively small, having just 94 blue straggler stars.