Nanfangquan station is located at the intersection of Nanhu Road and Xinglong Road in Binhu District, Wuxi. It is the terminus of Wuxi Metro Line 1. The station was completed and put into operation on September 28, 2019, as part of its southern extension.

Nanfangquan station is the terminal station of Line 1. It is a standard island platform with two underground floors. The station exits Gedaiqiao station, goes south through the Xidahe Green Belt, and ends at a station on Nanhu Road. After arriving at the station, the train returns via a switchback line.