Nanuet Senior High School is a public high school located in Nanuet, New York. It is formally known as "Nanuet Senior High School: The John P. Burke Building," named after the school's long-time principal. The Nanuet Senior High School houses grades 9–12. Its leadership team consists of a Principal and two Assistant Principals. In addition there are four guidance counselors, a Dean, a nurse, a student assistance counselor, a psychologist, a School Resource Officer, and department chairpersons. It is also a National Blue Ribbon School.

Nanuet's program offers courses in Art, English, French, Health, Math, Music, Physical Education, Science, Social Studies, Spanish and Technology.

Mascot:

Athletic teams are usually referred to as the "Nanuet Golden Knights."

Sports Teams:

• Charlie Adler: Known for his work on such cartoons as Tiny Toons and Rocko's Modern Life
• Joseph Glover: Professor of mathematics, past provost of the University of Florida.
• Kenneth Kiesler: American symphony orchestra and opera conductor
• Jamie Kurisko: American football tight end
• James Maritato: professional wrestler known for his work with World Wrestling Entertainment and Extreme Championship Wrestling.
• Greg Reitman: Environmentalist, film director, and producer.
• Ronald Thomas (cellist): American classical cellist
• Scott Wittman: known for his work as a director, lyricist, and writer for Broadway, concerts, and television.