Piazza Amedeo is an underground metro station that serve Line 2 on the Naples Metro. It went into service September 20, 1925, with the activation of the metropolitan service from Naples to Pozzuoli Solfatara (the so-called "underground").

The station has a pavilion made of reinforced concrete which leads through a long tunnel leading to the turnstiles and the docks. The station is located in the Rione Amedeo [it], in the heart of Naples' wealthy, near nightlife. It is also close to Via dei Mille, Via Calabritto and Piazza dei Martiri, which are lined with designer boutiques. The station is also well connected by Chiaia Funicular to Vomero.