Nebraska Highway 112 is a highway in southeastern Nebraska. Its western terminus is at the Kansas border where it continues as K-148 southwest of Odell. Its eastern terminus is at U.S. Highway 77 west of Blue Springs.

Nebraska Highway 112 begins at the border with Kansas, where it meets K-148. The highway heads north through farmland where it meets NE 8. It runs concurrently with NE 8 heading eastward through Odell. A few miles outside of Odell, the highway turns to the north again. It then continues northward until it terminates at US 77 west of Wymore.

The entire route is in Gage County.

Location	mi	km	Destinations	Notes
40th parallel north	0.00	0.00	K-148 west (All American Road) / State Line Road – Hanover	Nebraska–Kansas line; continuation into Kansas; former K-15E
Glenwood Township	3.04	4.89	N-8 west – Superior	South end of N-8 overlap
Paddock Township	9.08	14.61	N-8 east – Pawnee City	North end of N-8 overlap
Sicily Township	15.57– 15.69	25.06– 25.25	US 77 – Lincoln, Wymore	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

• List of state highways in Nebraska

• The Nebraska Highways Page: Highways 101 to 300