Nebraska Highway 58 is a highway in Nebraska. It has a length of 53 miles (85 km). Much of the route lies near the Loup River. The southern terminus is at an intersection with U.S. Highway 281 south of St. Paul. The northern terminus is at an intersection with Nebraska Highway 70 east of Arcadia.

Nebraska Highway 58 begins at U.S. Route 281 near St. Libory, heading west through farmland. At Dannebrog, the road forms a concurrency with Nebraska Highway 11 and heads southwest. The two roads split and Highway 58 heads west as it passes through Boelus. In Rockville, the road intersects Nebraska Highway 68 and turns northwest. In Loup City, Highway 58 becomes concurrent with Nebraska Highway 92 and turns west, intersecting Nebraska Highway 10. Past Loup City, Highway 58 splits from Highway 92 and continues north to its terminus near Arcadia at Nebraska Highway 70.

County	Location	mi	km	Destinations	Notes
Howard	St. Libory	0.00	0.00	US 281	Southern terminus
	Dannebrog	10.12	16.29	N-11 north (Naper Road)	South end of N-11 overlap
	​	15.17	24.41	N-11 south (Rose Road)	North end of N-11 overlap
Sherman	Rockville	27.33	43.98	N-68 west
	Loup City	39.33	63.30	N-92 east	South end of N-92 overlap
		41.58	66.92	R-82B east (O Street) / N-10 south – Sherman Reservoir State Recreation Area	Northern terminus of N-10; western terminus of R-82B
		42.30	68.08	N-92 west	North end of N-92 overlap
Valley	​	52.73	84.86	N-70	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

• Nebraska Roads: NE 41-60