Needle's Eye Wilderness is an 8,760-acre (35.5 km) wilderness area located approximately 20 miles (32 km) southeast of the town of Globe in Gila County in the U.S. state of Arizona.

The Mescal Mountains run northwest across the center of Needle's Eye Wilderness. The southwest flank of the range forms a dip slope of Paleozoic limestone more than 2,500 feet (762.0 m) high. The Gila River forms the Wilderness area's southern boundary as it cuts through the mountains in three narrow, 1,000-foot (304.8 m) deep canyons known as the Needle's Eye. A deep riparian zone covers the narrow river channel, forming the southern boundary of this area. Several small slickrock canyons bisect the Wilderness and connect to the Gila River.

Needle's Eye Wilderness is surrounded by the San Carlos Apache Indian Reservation to the north and south, and private lands to the east and west. Visitors must obtain permission in advance to access the Wilderness.

• List of Arizona Wilderness Areas
• List of U.S. Wilderness Areas
• Wilderness Act

• Needle's Eye Wilderness Area – U.S. Bureau of Land Management
• Needle's Eye Wilderness – Wilderness.net