Neusalza-Spremberg (pronunciation) is a town in the district Görlitz, in Saxony, Germany. It is situated on the border with the Czech Republic, on the river Spree, 6 km northwest of Ebersbach, and 17 km southeast of Bautzen.

Number of inhabitants

• 1925: 3,675
• 1939: 3,701
• 1946: 4,436
• 1950: 4,723
• 1964: 4,204
• 1990: 2,862
• 2000: 2,567
• 2005: 2,488
• 2006: 2,442
• 2007: 3,812 (after incorporation of Friedersdorf)
• 2009: 3,691
• 2012: 3,453
• 2013: 3,420
• 2015: 3,356

Mayor

Matthias Lehmann was reelected in June 2022.

Sons and daughters of the town and its district Friedersdorf

• Karl Thieme (1862-1932), theologian, extraordinary professor for Theology at the University of Leipzig
• Paul Reichelt (1898-1981), German General of the Wehrmacht and the Bundeswehr