Newburgh Lock and Dam is the 16th lock and dam on the Ohio River, located 776 miles (1,249 km) down stream of Pittsburgh.There are two locks. The main lock for commercial barge traffic that is 1,200 feet (370 m) long by 110 feet (34 m) wide, and the auxiliary lock is 600 feet (180 m) by 110 feet (34 m) wide.

Newburgh Lock and Dam replaced lock and dams 46 and 47 on the Ohio river.

• List of locks and dams of the Ohio River
• List of locks and dams of the Upper Mississippi River

• U.S. Army Corps of Engineers, Pittsburgh District
• U.S. Army Corps of Engineers, Huntington District
• U.S. Army Corps of Engineers, Louisville District