Newport National Bank is a historic bank building located at Newport, New Castle County, Delaware. It was built in 1864, and is a 2+1⁄2-story, five bay by three bay, brick building with a gable roof. It has a two-story service wing. The building was renovated in 1927 in the Colonial Revival style. The buildings contained both a residence and the bank, reflecting bank rules which required that the cashier and family reside in the building as a security measure.

It was added to the National Register of Historic Places in 1993.