The Bruce Highway touches the south-west boundary of North Isis (but does not enter it). At this point, the Isis Highway splits off and passes through the south-west corner of the locality and then forms the western boundary of the locality.
The land use is predominantly crop growing, mostly sugarcane, with grazing on native vegetation. There is a network of cane tramways in the locality to transport the harvested sugarcane to the local sugar mill.
The Isis railway line was extended from Childers to Cordalba, opening on 1 June 1896, with the following railway stations within this locality (from north to south):
In the 2016 census, North Isis had a population of 533 people.
In the 2021 census, North Isis had a population of 566 people.
Education
There are no schools in North Isis. The nearest government primary schools are Cordalba State School in neighbouring Cordalba to the west and Childers State School in neighbouring Childers to the south. The nearest government secondary school is Isis District State High School, also in Childers.
^"THE SUGAR INDUSTRY". The Capricornian. Vol. 20, no. 9. Queensland, Australia. 3 March 1894. p. 35. Archived from the original on 25 September 2024. Retrieved 3 August 2017 – via National Library of Australia.
^"QUEENSLAND SUGAR". Townsville Daily Bulletin. Vol. LIII, no. 108. Queensland, Australia. 6 May 1931. p. 11. Archived from the original on 25 September 2024. Retrieved 3 August 2017 – via National Library of Australia.
^"Advertising". The Brisbane Courier. No. 17, 697. Queensland, Australia. 3 October 1914. p. 1. Archived from the original on 25 September 2024. Retrieved 23 September 2024 – via National Library of Australia.
^"NEW STATE SCHOOLS". Daily Standard. No. 686. Queensland, Australia. 12 March 1915. p. 8 (SECOND EDITION). Archived from the original on 25 September 2024. Retrieved 23 September 2024 – via National Library of Australia.