Notre Dame Academy is a private, all-girls, college-preparatory Catholic school in Worcester, Massachusetts. The school is operated by the Roman Catholic Diocese of Worcester, and is the only all-girls, college-preparatory school in Central Massachusetts.

In 1950, the Sisters of Notre Dame de Namur were asked to establish an all-girls academy in Worcester. A year later, Notre Dame Academy was established within the Knollwood site.

Tuition for the 2023-2024 academic year is $17,040 for the high school, and $12,780 for grades 7-8.

• Jennifer Callahan, politician

• List of girls' schools in the United States
• List of high schools in Massachusetts

• Media related to Notre Dame Academy (Worcester, Massachusetts) at Wikimedia Commons
• Official Website