Nowa Brzeźnica [ˈnɔva bʐɛʑˈnit͡sa] is a village in Pajęczno County, Łódź Voivodeship, in central Poland. It is the seat of the gmina (administrative district) called Gmina Nowa Brzeźnica. It lies approximately 15 kilometres (9 mi) south-east of Pajęczno and 83 km (52 mi) south of the regional capital Łódź. It is located in the historic Sieradz Land.

It was a royal town, administratively located in the Radomsko County in the Sieradz Voivodeship in the Greater Poland Province of the Kingdom of Poland.