The Nyakijanda River (French: Rivière Nyakijanda) is a river in Burundi, a left tributary of the Nyabaha River.

The Nyakijanda River forms in the south of Ruyigi Province where it is fed by the Gihehe River and the Gisuma River. It flows north along the boundary between Gitega Province and Ruyigi Province and joins the Sanzu River, which flows from the east, to form the Nyabaha River.

The surroundings of Nyakijanda are a mosaic of agricultural land and natural vegetation. The area is quite densely populated, with 111 inhabitants per square kilometer as of 2016. The average annual temperature in the area is 19 °C (66 °F). The warmest month is September, when the average temperature is 22 °C (72 °F), and the coldest is April, with 18 °C (64 °F). Average annual rainfall is 1,321 millimetres (52.0 in). The rainiest month is December, with an average of 215 millimetres (8.5 in) of precipitation, and the driest is July, with 1 millimetre (0.039 in) of precipitation.

The Nyakijanda marsh is in the Commune of Itaba, southeast Gitega Province, between the Kirimo natural region to the west and the Buyogoma natural region to the east. Only the Nyakijanda marsh can be managed for agricultural purposes, growing rice or other crops. Almost all the commune's watercourses converge on the marshes of the Nyakijanda.

The falls on the Nyakijanda River have hydroelectric potential. As of 1984 a 250kW hydroelectric plant had been proposed on the Nyakijanda River about 3 km from Buhoro. A 2012 report by the Ministry of Energy and Mines identified two possible projects on the Nyakijanda: NYKI 012 at 2.8MW and NYKI 002 at 1.7MW A 2022 report identified a potential site on the Nyakijanda in the Nyamuyaga colline of the Commune of Butaganzwa, Ruyigi Province. The fall was 23 metres (75 ft) high with flow of 2.7 cubic metres per second (95 cu ft/s), giving potential of 487kW.

• List of rivers of Burundi

[[Category:Gitega Province}}