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O'Brien is an unincorporated community in Clay County, West Virginia, United States.

References

v t e Municipalities and communities of Clay County, West Virginia, United States
County seat: Clay
Town	Clay	Clay County map
Unincorporated communities	Adonijah Avoca Bentree‡ Bickmore Big Otter Bomont Booger Hole Clay Junction Cressmont Dille Dink Dorfee Duck Dundon Eakle Elkhurst Enoch Floe Fola Glen Harrison Hartland Independence Indore Ivydale Kidtown King Little Italy Lizemores Marne Maysel Morocco Mountain Home Nebo O'Brion Odessa Ossia Ovapa Paxton Porter Procious Queen Shoals‡ Rouzer Spread Swandale Triplett Two Run Valley Fork Varneytown Wallback‡ Whetstone Widen
Footnotes	‡This populated place also has portions in an adjacent county or counties
West Virginia portal United States portal