O'Connor Street is a downtown arterial road in Ottawa, Ontario, Canada. It is a north-south route, operating one way southbound, providing a key thoroughfare parallel to Bank Street.

The roadway begins at Wellington Street, at Parliament Hill, proceeding south towards the Queensway (Highway 417) where there is a westbound on-ramp. South of the Queensway, O'Connor continues as a local street in The Glebe neighbourhood until it reaches its southern terminus at Holmwood Avenue.

A two-way cycle track was built along the east side of the street in 2016.

(from North to South):

• Wellington Street
• Sparks Street
• Albert Street
• Slater Street
• Laurier Avenue
• Somerset Street
• Gladstone Avenue
• Catherine Street
• Highway 417 (Queensway)
• Isabella Street
• Fifth Avenue
• Holmwood Avenue

• Dominion-Chalmers United Church (O'Connor at Lisgar)
• High Commission of Australia in Ottawa
• High Commission of The Bahamas in Ottawa (at 50 O'Connor)
• Ottawa Curling Club (at 440 O'Connor)

• Ottawa Transportation Master Plan, see map 7 Central Area/Inner City Road Network