Oak Island, also known as the William Seabrook, Jr. House, is a historic plantation house located at Edisto Island, Charleston County, South Carolina. It was built about 1828–1831, and is a 2+1⁄2-story, five-bay, rectangular, central-hall, frame, weatherboard-clad residence with a projecting two-story rear pavilion. It features two, massive, interior chimneys with heavily corbelled caps and a one-story, wraparound hipped roof porch.

It was listed on the National Register of Historic Places in 1986.