State Route 335 (SR 335) is a north–south state highway in the southern portion of the U.S. state of Ohio. Its southern terminus is at US 52 in Sciotoville, a neighborhood within the city of Portsmouth, and its northern terminus is at SR 220 in Waverly where it has a wrong-way concurrency with US 23 and SR 104 for 0.35 miles (0.56 km).

Route description

Along the way, it intersects with SR 139 in Minford and SR 776 near Stockdale. It crosses SR 32 and SR 124 near Beaver.

This section needs expansion. You can help by adding to it. (January 2014)

History

SR 335 was commissioned in 1932, on it current route between Minford and Beaver. The highway was extended to Waverly in 1937. In 1939, the route was extended south to Portsmouth.

In 2003, the Ohio Department of Transportation (ODOT) commenced construction on a $1.8 million project to realign SR 335 from Dixon Mill Road to Gampp Lane in Scioto County east of the CSX railroad line. The realignment project was completed in May 2005.

Major intersections

County	Location	mi	km	Destinations	Notes
Scioto	Portsmouth	0.00– 0.42	0.00– 0.68	US 52 west / Gallia Street	No eastbound entrance to US 52
	Minford	9.28	14.93	SR 139
	Madison Township	15.39	24.77	SR 776 east	Western terminus of SR 776
Pike	Marion Township	21.25	34.20	SR 32 / SR 124 (James A. Rhodes Appalachian Highway) – Jackson, Cincinnati
	Waverly	42.06	67.69	US 23 north / SR 104 north (East Emmit Avenue) / Clough Street	Northern end of US 23 and SR 104 concurrency
		42.41	68.25	US 23 south / SR 104 south (West Emmit Avenue) / SR 220 (Market Street)	Southern end of US 23 and SR 104 concurrency
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Incomplete access