Opoku Ware School, often referred to as OWASS, is a public Catholic senior high school for boys, located in Santasi, a suburb of Kumasi, which is the capital of the Ashanti region of Ghana.

This article's list of alumni may not follow Wikipedia's verifiability policy. Please improve this article by removing names that do not have independent reliable sources showing they merit inclusion in this article AND are alumni, or by incorporating the relevant publications into the body of the article through appropriate citations. (June 2021)

• Kenneth Gilbert Adjei, former deputy NDC Minister of State
• Kwamena Ahwoi, former NDC Minister of State
• Owusu Afriyie Akoto, Minister for food and Agriculture
• Stephen Amoah, Member of Parliament for the Nhyiaeso Constituency
• James Kwesi Appiah (O 123) former head coach of the Ghana Black Stars
• George Boakye, former Chief of Air Staff
• Stephen Alan Brobbey, retired jurist; former Chief Justice of the Gambia and justice of the Supreme Court of Ghana
• Shadrack Osei Frimpong, founder of Cocoa360
• George Gyan-Baffour, Minister for Planning and Member of Parliament(Wenchi)
• Ohene Karikari, former national athlete and Africa's number one sprinter during his time
• John Kumah, Deputy Minister of Finance.
• Jacob Kwakye-Maafo, physician, surgeon and CEO of West End Clinic, Kumasi
• Christian Nsiah, Olympic athlete and Business Economics professor at Black Hills State University
• Paul Victor Obeng, mechanical engineer, Politician and former chairman of KNUST council
• Kevin Okyere, CEO, Springfield Group
• Anthony Akoto Osei, former Finance Minister and current MP for Old Tafo
• Ernest Owusu-Poku, former Inspector General of Police, Ghana
• Nana Akuoko Sarpong, traditional ruler of Agogo state, former politician
• Nana Otuo Siriboe, Chairman of the Council of State. The Omanhene of the Juaben traditional area.
• Amadu Sulley, Deputy Electoral Commissioner
• Yaw Tog, Musician, rapper
• Jacob Osei Yeboah, politician

• Navrongo Senior High School

• School's Website