OR 78 begins at an intersection with US 20 and US 395 in Burns and continues southeast through Crane and New Princeton to Burns Junction, where it ends at an intersection with US 95.
Intersection of US 95 and Oregon Route 78Steens Mountain from OR 78
History
OR 78 was assigned to the Burns-Crane Highway No. 24 when the Oregon route numbering system was initiated in 1932.