Oregon Route 52 (OR 52) is a very short Oregon state highway that runs from OR 201 at Payette Junction, Oregon, to the Snake River (the Idaho state line) at Payette, Idaho. It is a continuation of ID 52 and was once signed as Oregon Route 90. OR 52 consists of the Payette Spur No. 492 (see Oregon highways and routes).

OR 52 begins at an intersection with OR 201 at Payette Junction and continues south to the Idaho state line at Payette, Idaho, where it continues as ID 52.

The Payette Spur was designated OR 90 in 1932 and renumbered OR 52 in 1952.

The entire route is in Malheur County.

Location	mi	km	Destinations	Notes
​	19.65	31.62	OR 201 – Weiser, Baker City, Ontario
Snake River	21.23– 21.30	34.17– 34.28	Payette Bridge; Oregon–Idaho state line
			SH-52 east – Payette	Continuation into Idaho
1.000 mi = 1.609 km; 1.000 km = 0.621 mi

• "Olds Ferry-Ontario Highway No. 455"