Osseo Senior High School is a four-year public high school located in Osseo, Minnesota, United States on 317 2nd Ave. NW. The principal is Sara Vernig. Osseo Senior High School is a part of the Osseo Area School District 279 and is one of three four-year high schools in the district.

Osseo Senior High opened its doors in 1924 as the first high school built by the Osseo School District.

According to the Minnesota Department of Education, the racial makeup of Osseo during the 2023-24 School year was as follows:

African-American: 35.7%
           White: 27.7%
           Asian: 16.0%
        Hispanic: 11.9%

Two or More Races: 6.4%

 Native American:  2.1% 
Pacific Islander:  0.1%
           Other:  0.1%

• Calvin Bloom - Professional wrestler signed to the WWE as Von Wagner
• Mike Enos - Professional wrestler
• Joe Jensen - Professional hockey player who played for the Carolina Hurricanes of the NHL
• Nash Jensen - Professional football player
• Trent Klatt - former NHL player who played for the Philadelphia Flyers, Minnesota North Stars, Dallas Stars, Vancouver Canucks and Los Angeles Kings
• Kevin Kling - commentator for National Public Radio and acclaimed storyteller and Playwright
• James Martinez - Olympic Greco-Roman Wrestling Bronze Medalist, Lightweight
• Erin Koegel - state representative
• Travis Morin -Former NHL/AHL, professional hockey player for the Dallas Stars. Was drafted by the Washington Capitols and played for their minor league teams the South Carolina Stingrays and the Hershey Bears
• Jerry Newton - state representative
• Caleb Truax - Professional Boxer, IBF Super Middleweight Champion, Super Middleweight 23-1-1
• Claudia Meier Volk, American politician who served in the Minnesota House of Representatives
• Jake Wheatley - Pennsylvania state representative

• Official website