Ōtemachi Station (大手町駅, Ōtemachi-eki) is a major subway station in Chiyoda, Tokyo, Japan, jointly operated by Tokyo Metro and Toei Subway. It is served by five lines, more than any other station on the Tokyo underground network, and is thus the biggest subway station in Tokyo. It is Tokyo Metro's second busiest station, after Ikebukuro.

Ōtemachi Station is within walking distance (either at street level or via underground passages) of Tokyo Station.

• Tokyo Metro
  • T Tozai Line
  • M Marunouchi Line
  • Z Hanzōmon Line
  • C Chiyoda Line
• Toei Subway
  • I Mita Line

1	M Marunouchi Line	for Ginza, Shinjuku, and Ogikubo
2	M Marunouchi Line	for Ochanomizu and Ikebukuro
3	T Tozai Line	for Nishi-funabashi JB Sōbu Line (Local) for Tsudanuma TR Tōyō Rapid Railway Line for Toyo-Katsutadai
4		for Takadanobaba and Nakano JB Chūō Line (Local) for Mitaka
5	C Chiyoda Line	for Kasumigaseki and Yoyogi-uehara Odakyu Odawara Line for Hon-Atsugi and Isehara
6		for Shin-ochanomizu, Kita-senju, Ayase, and Kita-ayase JL Jōban Line (Local) for Abiko and Toride
7	Z Hanzōmon Line	for Kudanshita and Shibuya DT Tokyu Den-en-toshi Line for Chuo-rinkan
8		for Kinshicho and Oshiage TS Tobu Skytree Line for Tōbu-dōbutsu-kōen TI Tobu Isesaki Line for Kuki TN Tōbu Nikkō Line for Minami-Kurihashi

• 
  Marunouchi Line platform 1 (July 2022)
• 
  Marunouchi Line platform 2 (July 2022)
• 
  Tozai Line platform (July 2022)
• 
  Chiyoda Line platform (July 2022)
• 
  Hanzomon Line platform (July 2022)

1	I Mita Line	for Shirokane-takanawa and Meguro MG Meguro Line for Musashi-Kosugi and Hiyoshi Sotetsu Main Line for Ebina via the Tokyu/Sotetsu Shin-Yokohama Line Sotetsu Izumino Line for Shōnandai via the Tokyu/Sotetsu Shin-Yokohama Line
2		for Sugamo and Nishi-takashimadaira

• 
  Mita Line platform (June 2022)

The station opened on July 20, 1956 as a station on the Marunouchi Line. The Tōzai Line platforms opened on October 1, 1966 as a terminus of the line from Nakano, becoming through platforms on September 14, 1967. The Chiyoda Line platforms opened on December 20, 1969 as the terminus of the line from Kita-Senju; they became through platforms on March 20, 1971. The Mita Line platforms opened on June 30, 1972, and the Hanzōmon Line platforms on January 26, 1989.

With the exception of the Mita Line, the station facilities of the remaining lines were inherited by Tokyo Metro after the privatization of the Teito Rapid Transit Authority (TRTA) in 2004.

• Marunouchi Building
• Otemachi Tower
• Palace Hotel
• Shin-Marunouchi Building
• Tokyo Imperial Palace
• Yomiuri Shimbun Building

• Otemachi Station information (Tokyo Metro) (in English)
• Otemachi Station information (Toei) (in English)

35°41′05″N 139°45′57″E / 35.684699°N 139.765964°E / 35.684699; 139.765964