Pętkowo Wielkie [pɛntˈkɔvɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Zaręby Kościelne, within Ostrów Mazowiecka County, Masovian Voivodeship, in east-central Poland. It lies approximately 6 kilometres (4 mi) south-east of Zaręby Kościelne, 22 km (14 mi) south-east of Ostrów Mazowiecka, and 98 km (61 mi) north-east of Warsaw.