P.S. Senior Secondary School is situated in the Mylapore area of Chennai, India. Most students graduating enter higher education institutions especially engineering institutions like NIT Tiruchi and Anna University. It is a CBSE school in Chennai city.

The school was founded by Mr. Pennathur Subramania Iyer. The emphasis of the Tamil Nadu state Government on Tamil being used as the medium of instruction was causing a fall in Tamil Nadu's share of employment in all-India and central services and in the national science and technology establishments. In 1973 P.S. Charities promoted the establishment of English medium schools. The P.S. Educational Society started, on 9 June 1976, P.S. Senior Secondary School, starting with standards I-VII from 1976.

P.S.Senior Secondary School (affiliated with the CBSE), was started to help the public and very importantly, the employees of the central government and in the matter of the educational affairs of their children. The school is located in a spacious campus with well-equipped science laboratories and libraries. The school has a playground which spans over 10,000 square metres and a lot of importance is given to sports. The school also houses an art center, which focuses on identifying and nurturing talent.

This decision was passed in the court case at the Madras High Court, labelled Dr. S. Anandalakshmy versus Government of India CBSE.

The school is situated on a 3.2-acre (13,000 m) campus with a playground as its center, divided into four blocks:

• Administration: consists of the principal's office, the computer science laboratory, the electrical gadgets lab, the seminar and examination halls, the audio visual room and the mathematics laboratory.
• Science: houses the classrooms for middle and senior school students, the Science and Typewriting labs and the library.
• Yoga: extracurricular activities such as music and dance and indoor sports.
• Primary, Middle, Secondary and Senior Secondary blocks are there with its separate staff rooms.

There is a kindergarten block with a small playground.

The main school playground has a badminton court, three volleyball-cum-throwball courts, a basketball court, a football court, and two cricket nets.

Wins at the International and National Olympiads from 1995 to 2010:

• Mathematics Olympiad

• 1995–1996, Silver Medal (Toronto, Canada)
• 1999–2000, Silver Medal (Bucharest, Romania)

• Biology Olympiad

• 1999–2000 Silver Medal (Antalya, Turkey)
• 2001–2002 Bronze Medal (Jurmala, Latvia)
• 2002–2003 Bronze Medal (Minsk, Belarus)
• 2004–2005 Gold Medal (Beijing, China)
• 2007–2008 Silver Medal (Mumbai, India)

• Chemistry Olympiad

• 2001–2002 Bronze Medal (Groningen, Netherlands)
• 2002–2003 Gold Medal (Athens, Greece)
• 2002–2003 Silver Medal (Athens, Greece)
• 2005 Silver Medal (Taipei, Taiwan)
• 2004 Gold Medal - National Level Olympiad
• 2004 Gold Medal - National Level Olympiad
• 2009 Top 10 Medal at National Level Olympiad

• International Olympiad for Informatics

• 2006 Bronze Medal (Merida, Mexico)
• 2009 Silver Medal (Bulgaria)

• CBSE Under 19 National Girls Football Championship 2013-2014 - Bronze Medal
• Commonwealth Chess Championship (2008) Boys Under-14 – Gold Medal
• World Youth Chess Championship 2009
• Table Tennis State Champion in Junior Girls Category
• Women State Ranking No. 2
• TNCA U16 boys cricket tournament Winners
• CBSE Under 19 National Girls Football Championship- Winner

The school has two of its students who have qualified for the finals of the World Scholars Cup to be held at Yale University USA. The school has four of its students in the under-16 boys cricket team.

PS Senior is one of the top schools in Chennai in culturals.

• PS has secured first place in 6 of 8 cultural fests it participated in the year 2017–present.
• PS Senior also hosts a cultural fest named Scintilation.

• S. Sowmya
• Haricharan
• Savitha Sastry
• Aditi Balan
• Samanth Subramanian
• Arvind Swamy
• Rita Thyagarajan

• Official school website