Pacific Reef is a coral reef located within the Florida Keys National Marine Sanctuary and also within Biscayne National Park. Unlike many reefs within the National Marine Sanctuary, this reef is not within a Sanctuary Preservation Area (SPA). It is south of Ajax Reef.

The Pacific Reef Light is still operational at Pacific Reef.

• NOAA National Marine Sanctuary Maps, Florida Keys East
• NOAA Navigational Chart 11463