Pala Casino Spa Resort is a casino hotel and spa in Pala, California, on the Pala Indian Reservation northeast of San Diego. It is owned and operated by the Pala Band of Mission Indians, a federally recognized tribe.

The casino has 86,000 square-feet of casino floor, 2,250 slot machines, 84 table games, 9 restaurants, an 11,000-square-foot (1,000 m) day spa, and 4 entertainment venues. The hotel has 500 rooms and 82 suites.

In March 2000, construction began on the $115 million Pala Casino, which opened in April, 2001. On August 19, 2003, Pala Casino Spa & Resort opened with 500 rooms, a spa, and a conference center. The project cost around $105 million to complete.

There are nine restaurants located within Pala Casino Spa Resort.

• List of casinos in California
• List of casino hotels

33°21′47″N 117°05′02″W / 33.363°N 117.084°W / 33.363; -117.084