Papalote is an unincorporated community in Bee County, in the U.S. state of Texas. According to the Handbook of Texas, the community had a population of 70 in 2000. It is located within the Beeville micropolitan area.

Papalote was first settled on Papalote Creek after land grants were given by Mexico to its early settlers. The area was split into three settlements: Lower, Central, and Upper Papalote, but the three merged into one settlement around the mid-1880s.

Several schools were established throughout Papalote's history, such as schools in Lower Papalote. It is currently part of the Skidmore-Tynan Independent School District.