The George Parks Highway (numbered Interstate A-4 and signed Alaska Route 3), usually called simply the Parks Highway, runs 323 miles (520 km) from the Glenn Highway 35 miles (56 km) north of Anchorage to Fairbanks in the Alaska Interior. The highway, originally known as the Anchorage-Fairbanks Highway, was completed in 1971, and given its current name in 1975.

The highway, which mostly parallels the Alaska Railroad, is one of the most important roads in Alaska. It is the main route between Anchorage and Fairbanks (Alaska's two largest metropolitan areas), the principal access to Denali National Park and Preserve and Denali State Park, and the main highway in the Matanuska-Susitna Valley. The route's Interstate designation is not signed; rather, its entire length is signed as Alaska Route 3.

It is a common misconception that the name "Parks Highway" comes from the road's proximity to the Denali state and national parks; it is in fact in honor of George Alexander Parks, governor of the Territory of Alaska from 1925 to 1933. However, the aptness of the name was recognized when it was chosen.

Mileposts along the Parks Highway do not begin with 0 (zero). Instead, they begin with Mile 35 (km 56), continuing the milepost numbering of the Glenn Highway where the two highways intersect near Palmer. The 0 (zero) mile marker for the Glenn Highway is at its terminus in downtown Anchorage at the intersection of East 5th Avenue and Gambell Street. Thus mileposts along the Parks Highway reflect distance from Anchorage, which is not actually on the Parks Highway.

There are two sections of the highway that are built to freeway standards. These include an area near the highway's intersection with the Glenn Highway in Palmer and a stretch known as the Robert J. Mitchell Expressway in Fairbanks leading to the highway's junction with the Richardson Highway (AK 2).

Interstate A-4
Location	Palmer to Fairbanks
Length	323.69 mi (520.93 km)
Existed	1976–present

George Parks Highway is part of the unsigned part of the Interstate Highway System as Interstate A-4.

In the "Mile" column, the first number is the actual mileage of the Parks Highway, and the second mile is based on the mileposts along the highway itself.
All exits are unnumbered.

Borough	Location	mi	km	Destinations	Notes
Matanuska-Susitna	Gateway	0.00– 35	0.00– 56	AK-1 south (Glenn Highway)	Interchange, East end of Wasilla freeway section
				Trunk Road	Interchange
		2.58– 37.58	4.15– 60.48	Fairview Loop / Hyer Road	Interchange
	Lakes			Seward-Meridian Parkway	Interchange
	Wasilla	3.66– 38.66	5.89– 62.22	West end of Wasilla freeway section
				Palmer-Wasilla Highway
				Museum Drive	To New Wasilla Airport
	Houston			Big Lake Road	To Big Lake
	Denali State Park			Entering Denali State Park
				Exiting Denali State Park
Denali	Cantwell			AK-8 east (Denali Highway)	Denali Highway continues a short distance west to the Cantwell Airport.
	Denali National Park and Preserve			Entrance to Denali National Park and Preserve
Fairbanks North Star	College			West end of Fairbanks freeway section
		317.65– 352.62	511.21– 567.49	Geist Road / Chena Pump Road—University of Alaska	Interchange
		318.81– 353.81	513.07– 569.40	Airport Way west— Fairbanks International Airport	Interchange; Beginning of the Robert Mitchell Expressway
		318.81– 353.81	513.07– 569.40	Airport Way east	Interchange; Southbound exit is via Old Airport Road
		319.73– 354.73	514.56– 570.88	University Avenue
	Fairbanks	321.94– 356.94	518.11– 574.44	Peger Road
		322– 357.95	518– 576.06	Lathrop Street
				Cushman Street / Old Richardson Highway	Interchange; Northbound exit and southbound entrance; Access via 30th Avenue from northbound roadway and via 28th Avenue from southbound roadway
		323– 358	520– 576	AK-2 (Richardson Highway) – North Pole, Delta Junction	Interchange; Northbound exit and southbound entrance
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Incomplete access

• 
  The multi-lane Parks Highway is seen at right as it passes by a downtown Wasilla business.
• 
  The highway's bridge over Hurricane Gulch.
• 
  The Parks Highway near Hurricane, Alaska.
• 
  Milepost 238 signpost in McKinley Park. The signpost is located in a turnout adjacent to a bridge crossing the Nenana River and near the entrance to Denali National Park.
• 
  View of the Parks Highway in early autumn, looking northbound.
• 
  The northern terminus of the highway in Fairbanks. View looking easterly from just west of the South Cushman Street overpass.

• U.S. roads portal
• Alaska portal
• Tornio Highway

• A journey down the George Parks Highway Archived 2012-02-07 at the Wayback Machine