Pelzer Presbyterian Church is a historic Presbyterian church located at 13 Lebby Street in Pelzer, Anderson County, South Carolina. It was built in 1896, and is a rectangular Akron Plan church building with a gable front roof and sheathed in weatherboard. It features impressive stained and leaded glass windows and a Gothic arch entrance. A two-story, five-sided Sunday school classroom addition was built in 1905.

It was built in 1896 and added to the National Register in 1993.